more background rationale
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README.md
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README.md
@@ -22,16 +22,22 @@ A comprehensive description of the spatiotemporal activity patterns in the immat
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### Previous work
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reference | FOV info | figure snapshot
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[Ackman et al][#Ackman:2012] | 3 x 4 mm FOV WF-MCI in V1, V2, and SC P3-P9 mouse | 
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[Siegel et al.][#Siegel:2012] | 219x180 µm FOV 2P-MCI in visual cortex | 
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[Chiu & Weliky][#Chiu:2001] | linear MEA covering a 3.2 mm strip across visual cortex Corr activity observed between cortical patches separated by mean distance of 1 mm | 
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[Colonnese et al.][#Colonnese:2010] | single pulled electrodes in V1 or linear MEA (16 site silcon probe, 4sites x 4shanks, with 200µm separation, 600µm total | 
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[Hanganu et al][#Hanganu:2006] | single electrodes or 4 shank linear MEAs placed in each hemisphere (0.5-1.0mm spacing, for 1.5-3.0mm total) | 
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[Yang et al][#Yang:2012a] | 2.6 x 2.6 mm FOV, VSD imaging in S1 cortex P0-7 rat. Spont and evoked activity in C2 barrel. 8shank x 4site silicon probe linear MEA (200µm separation, 1.4mm total) | 
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[Rochefort et al][#Rochefort:2009] | 100x70µm FOV 2P-MCI in mouse visual cortex at P11 | 
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reference | FOV info | figure snapshot
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[Chiu & Weliky][#Chiu:2001] | linear MEA covering a **3.2 mm strip** across visual cortex Corr activity observed between cortical patches separated by mean distance of 1 mm | 
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[Hanganu et al][#Hanganu:2006] | single electrodes or 4 shank linear MEAs placed in each hemisphere (0.5-1.0mm spacing, for **1.5-3.0mm total**) | 
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[Rochefort et al][#Rochefort:2009] | 100x70µm FOV 2P-MCI in mouse visual cortex at P11 | 
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[Colonnese et al.][#Colonnese:2010] | single pulled electrodes in V1 or linear MEA (16 site silcon probe, 4sites x 4shanks, with 200µm separation, **600µm total** | 
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[Siegel et al.][#Siegel:2012] | **219x180 µm FOV** 2P-MCI in visual cortex | 
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[Ackman et al][#Ackman:2012] | **3.0 x 4.0 mm FOV** WF-MCI in V1, V2, and SC P3-P9 mouse | 
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[Leinekugel et al][#Leinekugel:2002] | P4-6 rat hippocampus, cortex, 8 tip linear MEA (tungsten wires), 100-300µm vertical tip separation | 
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[Khazipov et al][#Khazipov:2004a] | P1-6 rat somatosensory cortex, single electrode MUA and PC | 
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[Yang et al][#Yang:2009] | 4x4 linear MEA 200µm spacing, **600µm total**, bilaterally in S1 barrel cortex | 
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[Yang et al][#Yang:2012a] | **2.6 x 2.6 mm FOV**, VSD imaging in S1 cortex P0-7 rat. Spont and evoked activity in C2 barrel. 8shank x 4site silicon probe linear MEA (200µm separation, 1.4mm total) | 
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[Golshani et al][#Golshani:2009] | 2P-MCI in mouse S1 **478 x 186 µm FOV** | 
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monkey and human | EEG performed prenatally [#Vanhatalo:2005][#Tolonen:2007], no fMRI prenatally, (or infant?) but has been done in children for resting state connectivity |
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**Conclusion:** The 'meso–macro' scale activity patterns within and between the developing cortical hemispheres have not been reported in any species.
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### Future work
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[#Rochefort:2009]: Rochefort, N. L., Garaschuk, O., Milos, R.-I., Narushima, M., Marandi, N., Pichler, B., Kovalchuk, Y., and Konnerth, A. (2009). Sparsification of neuronal activity in the visual cortex at eye-opening, Proc Natl Acad Sci U S A, 106(35), 15049-54
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[#Leinekugel:2002]: Leinekugel, X., Khazipov, R., Cannon, R., Hirase, H., Ben-Ari, Y., and Buzsáki, G. (2002). Correlated bursts of activity in the neonatal hippocampus in vivo, Science, 296(5575), 2049-52
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[#Khazipov:2004a]: Khazipov, R., Sirota, A., Leinekugel, X., Holmes, G. L., Ben-Ari, Y., and Buzsáki, G. (2004). Early motor activity drives spindle bursts in the developing somatosensory cortex, Nature, 432(7018), 758-61
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[#Golshani:2009]: Golshani, P., Gonçalves, J. T., Khoshkhoo, S., Mostany, R., Smirnakis, S., and Portera-Cailliau, C. (2009). Internally mediated developmental desynchronization of neocortical network activity, J Neurosci, 29(35), 10890-9
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